History

2012

Needs

  • Provide integrated analysis environment for Metabolomics
  • Emerging field

Bioinformatics platform

  • Skills and experiences (e.g. NGS)

Which tools /software?

  • Build data analysis workflow
  • Traceability
  • High Performance Computing resources
  • Data and pipeline sharing
  • Galaxy - perfect tool? Internship : 1 month – june 2012

V1

  • Proof of Concept: XCMS package integration in a few weeks!

2013

Funding

  • Brittany : 2 Y (Workflow4Metabo)
    • Misharl Monsoor
  • ABiMS
    • Pierre Péricard & Gildas Le Corguillé
  • Auvergne : 2 Y. (FLAME)
    • Marion Landi
  • PFEM
    • Franck Giacomoni & JF Martin

V2

  • Correlation analysis & Statistical : Hierarchical Clustering, ANOVA, PCA
  • New components : Quality control, Normalization, Annotation

2014

Institut Français de Bio-informatique / MetaboHUB

  • Change of scale: partners number, regional/national, etc.
  • Greater synergy
  • Sharing : internal training & transfer of skills and knowledge
  • Complementarity of skills : Metabolomics / Bioinformatics

V3

  • Virtual Research Infrastructure
  • Several and new tools!
    • Quality control
    • Normalization
    • Statistical Analysis
    • Annotation

2015

New collaboration with CNRS IRISA and LINA labs :

  • Creation of GC-MS modules